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Welcome

Welcome to the Immuno-modulatory Biomaterials Laboratory (IMBL) in the Department of Biomedical Engineering at the University of Florida, directed by Associate Professor Jamal S. Lewis.

 

The Immuno-modulatory Biomaterials Laboratory focuses on the development of novel biomaterial systems that can manipulate the immune system. Our goal is to design the next generation of immunotherapeutics for applications in immune-related diseases. This multidisciplinary work incorporates aspects of biomaterials engineering, drug delivery, immunology, biochemistry and cell biology.

 

Currently, research efforts in the Lewis lab are centered on:

 

  • Development of a particulate platform system for autoimmune disease therapy​

  • Elucidating latent, Immunosuppressive Nature of Poly(lactic-co-glycolic acid) Microparticles

 

  • Understanding controlled non-lytic exocytosis in phagocytic cells

 

  • Uncovering the role of dendritic cells in the foreign body response to materials

Team
Prof. Jamal Lewis

Prof. Jamal Lewis

Dr. Krishna Gaddam

Dr. Krishna Gaddam

Allen Tu

Allen Tu

Rian Harriman

Rian Harriman

Deanna Diaz

Deanna Diaz

Clinton Smith

Clinton Smith

Kevin Smith

Kevin Smith

Zhenyu Wang

Zhenyu Wang

Neeraj Senthil

Neeraj Senthil

Patricia Arizaleta

Patricia Arizaleta

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Immuno-modulatory Biomaterials Laboratory
IMBL at Work

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Research Videos and Images

Poly(D,L-lactic-co-glycolic) MP

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Dual-Fluorophore Vomocytosis Reporter System Update

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PLGA MPs (SEM)

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Poly(D,L-lactic-co-glycolic) MP

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All Videos

All Videos

All Videos
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Phagocytic Uptake of DiD stained MPs by DCs

Phagocytic Uptake of DiD stained MPs by DCs

00:07
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Vomocytosis

Vomocytosis

00:16
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RA Remission Using Dual Microparticle System

RA Remission Using Dual Microparticle System

00:34
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