Publications

35. Tu AB, Lewis JS. Biomaterial-based immunotherapeutic strategies for rheumatoid arthritis. Drug Deliv Transl Res. 2021 Aug 19:1–23. doi: 10.1007/s13346-021-01038-w. Epub ahead of print.

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34. Harriman R, Lewis JS. Bioderived materials that disarm the gut mucosal immune system: Potential lessons from commensal microbiota. Acta Biomater. 2021 Jun 5:S1742-7061(21)00355-X. doi: 10.1016/j.actbio.2021.05.045. Epub ahead of print. PMID: 34098091.

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33. Kakwere H, Zhang H, Ingham ES, Nura-Raie M, Tumbale SK, Allen R, Tam SM, Wu B, Liu C, Kheirolomoom A, Fite BZ, Ilovitsh A, Lewis JS, Ferrara KW. Systemic Immunotherapy with Micellar Resiquimod-Polymer Conjugates Triggers a Robust Antitumor Response in a Breast Cancer Model. Adv Healthc Mater. 2021 May;10(10):e2100008.

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32. Carstens MR, Wasserfall CH, Acharya AP, Lewis J, Agrawal N, Koenders K, Bracho-Sanchez E, Keselowsky BG. GRAS-microparticle microarrays identify dendritic cell tolerogenic marker-inducing formulations. Lab Chip. 2021 Aug 4.

Learn more

31. Allen R, Ivtchenko E, Thuamsang B, Sangsuwan R, Lewis JS. Polymer-loaded hydrogels serve as depots for lactate and mimic "cold" tumor microenvironments. Biomater Sci. 2020 Oct 1. doi: 10.1039/d0bm01196g. Epub ahead of print. PMID: 33000781.

Learn more

30. Sangsuwan, R., Thuamsang, B., Pacifici, N. et al. Lactate Exposure Promotes Immunosuppressive Phenotypes in Innate Immune Cells. Cel. Mol. Bioeng. (2020). https://doi.org/10.1007/s12195-020-00652-x

Learn more

29. Pacifici, N., Bolandparvaz, A., & Lewis, J. S. (2020). Stimuli-Responsive Biomaterials for Vaccines and Immunotherapeutic Applications. Advanced therapeutics, 2000129. Advance online publication. https://doi.org/10.1002/adtp.202000129

Learn more

28. Keselowsky, B. G., Acharya, A., & Lewis, J. S. (2020). Innate and Adaptive Immunity: The Immune Response to Foreign Materials. In Biomaterials Science (pp. 747-776). Academic Press. doi: https://doi.org/10.1016/B978-0-12-816137-1.00049-0

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27. Bolandparvaz, A., Vapniarsky, N., Harriman, R., Alvarez, K., Saini, J., Zang, Z., ... & Lewis, J. S. Biodistribution and Toxicity of Epitope‐functionalized Dextran Iron Oxide Nanoparticles in a Pregnant Murine Model. Journal of Biomedical Materials Research Part A, 2020, doi: https://doi.org/10.1002/jbm.a.36893.

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26. Cruz-Acuña, M., Pacifici, N., & Lewis, J. S. Vomocytosis: Too Much Booze, Base, or Calcium? mBio, 2019, doi: 10.1128/mBio.02526-19

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25. Lewis, J. S., Stewart, J. M., Marshall, G. P., Carstens, M. R., Zhang, Y., Dolgova, N. V., ... & Atkinson, M. A. "Dual-Sized Microparticle System for Generating Suppressive Dendritic Cells Prevents and Reverses Type 1 Diabetes in the Nonobese Diabetic Mouse Model" ACS Biomaterials Science & Engineering, 2019, doi: 10.1021/acsbiomaterials.9b00332

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24. Bolandparvaz, Amir et al. “Towards a nanoparticle-based prophylactic for maternal autoantibody-related autism” Nanomedicine: Nanotechnology, Biology and Medicine, 2019, doi.org/10.1016/j.nano.2019.102067

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23. Allen, Riley et al. “Combinatorial, Microparticle-Based Delivery of Immune Modulators Reprograms the Dendritic Cell Phenotype and Promotes Remission of Collagen-Induced Arthritis in Mice.” ACS Bio Materials, 2019, doi: 10.1021/acsabm.9bOOO92.

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22. Kakwere, Hamilton, et al. “Unimicellar Hyperstars as Multi-Antigen Cancer Nanovaccines Displaying Clustered Epitopes of Immunostimulating Peptides.” Biomaterials Science, 2018, doi:10.1039/c8bm00891d.

Learn more

21. Riley P. Allen, Amir Bolandparvaz, Jeffrey A. Ma, Vishal A. Manickam, and Jamal S. Lewis. Latent, Immunosuppressive Nature of Poly(lactic-co-glycolic acid) Microparticles. ACS Biomaterials Science & Engineering 2018 4 (3), 900-918. DOI: 10.1021/acsbiomaterials.7b00831

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20. Lawrence Fernando, Jamal S. Lewis, Brian C. Evans, Craig Duvall, Benjamin G. Keselowsky. Formulation and characterization of poly(propylacrylic acid) / poly(lactic-coglycolic acid) blend microparticles for pH-dependent membrane disruption and cytosolic delivery. Journal of Biomedical Materials Research Part A. November 2017. DOI:10.1002/jbm.a.36298

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19. Hamilton Kakwere† , Elizabeth S. Ingham†, Riley Allen†, Lisa M. Mahakian†, Sarah M. Tam†, Hua Zhang†, Matthew T. Silvestrini†, Jamal S. Lewis† , and Katherine W. Ferrara*†, PToward Personalized Peptide-Based Cancer Nanovaccines: A Facile and Versatile Synthetic Approach.

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18. Yang, L., Bracho-Sanchez, E., Fernando, L., Lewis, J.S., Carstens, M., Duvall, C., Keselowsky, B. Poly(2-propylacrylic acid) / poly(lactic-co-glycolic acid) blend microparticles as a targeted antigen delivery system to direct either CD4+ or CD8+ T cell activation. Bioengineering and Translational Medicine. Accepted – June 2017.

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17. Keselowsky, B.G., Lewis, J.S. Dendritic cells in the host response to implanted materials. Seminars in Immunology. 2017 May: S1044-5323(16)30111-7. doi: 10.1016/j.smim.2017.04.002.

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16. Zaveri, T. D., Dolgova, N. V., Lewis, J. S., Hamaker, K., Clare-Salzler, M. J., & Keselowsky, B. G. (2016). Macrophage integrins modulate response to ultra-high molecular weight polyethylene particles and direct particle-induced osteolysis. Biomaterials. doi:10.1016/j.biomaterials.2016.10.038

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15. Lewis, J. S., & Allen, R. P. (2016). An introduction to biomaterial-based strategies for curbing autoimmunity. Experimental Biology and Medicine, 241(10), 1107-1115. doi:10.1177/1535370216650294

Learn more

14. Abhinav P Acharya, Matthew Carstens, Jamal S. Lewis, Natalia Dolgova, Chang Qing Xia, Michael Clare-Seller, Benjamin G. Keselowsky. A cell-based microarray to investigate the combinatorial effects of microparticle-encapsulated adjuvants on dendritic cell activation. In press – Journal of Materials Chemistry B. DOI: 10.1039/C5TB01754H.

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13. Young Mee Yoon, Jamal S. Lewis, Matthew R. Carstens, Martha Campbell-Thompson, Clive H. Wasserfall, Mark A. Atkinson, Benjamin G. Keselowsky. A combination Hydrogel microparticle-based vaccine prevents type 1 diabetes in non-obese diabetic mice. Scientific Reports. August 2015. Vol. 5; #13155 (doi:10.1038/srep13155).

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12. Lewis, J.S, Dolgova, N.V., Zhang, Y., Xia, C.Q., Wasserfall, C.H., Atkinson, M.A., Clare-Salzler, M.J., Keselowsky, B.G. (In press, 2015) A combination dual-sized microparticle system modulates dendritic cells and prevents type 1 diabetes in prediabetic NOD mice. Clinical Immunology. (doi:10.1016/j.clim.2015.03.023)

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11. Toral Zaveri, Jamal S. Lewis, Natalia Dolgova, Michael Clare-Salzler, Benjamin G. Keselowsky. Integrin-Directed Modulation of Macrophage Response to Biomaterials. Biomaterials. January 2014. Vol. 35; 3504 –3515.

Learn more

10. Jamal S. Lewis, Chris Roche, Ying Zhang, Benjamin G. Keselowsky. Microsphere technology offers combinatorial and local drug delivery to dendritic cells for enhancement of suppressive function. J. Mater. Chem. B. 2:2562-2574. (DOI: 10.1039/C3TB21460E). January 2014.

Learn more

9. Jamal S. Lewis, Krishnendu Roy, Benjamin G. Keselowsky. Materials that harness and modulate the immune system. MRS Bulletin. January 2014. Vol. 39; 25 – 34.

Learn more

8. Jamal S. Lewis, Natalia V. Dolgova, Thomas J. Chancellor, Abhinav A. Acharya, Jerome V. Karpiak, Tanmay P. Lele, Benjamin G. Keselowsky. Dendritic cell activation is influenced by cyclic mechanical strain when cultured on adhesive substrates. Biomaterials. August 2013. Vol. 34; 9063 – 9070

Learn more

7. Abhinav P. Acharya, Jamal S. Lewis, Benjamin G. Keselowsky. High-throughput Parallel Particle Production for Combinatorial Encapsulation of Hydrophobic Molecules. Biomaterials. April 2013. Vol. 34; 3422 – 3430

Learn more

6. Jamal S. Lewis, Patrick C. Crooks, Toral Zaveri, Benjamin G. Keselowsky. Microparticle surface modification approaches for efficient dendritic cell-targeting drug delivery for auto-immune vaccine applications. Biomaterials. June 2012. Vol. 33; 7221 – 7232

Learn more

5. J S Lewis, S D Gittard, R J Narayan, C J Berry, R L Brigmon, R Ramamurti, R N Singh. Assessment of Microbial Biofilm Growth on Nanocrystalline Diamond Coatings Using a CDC Biofilm Reactor. J. Manuf. Sci. Eng. June 2010 132, 030919

Learn more

4. Evelyn Bracho-Sanchez, Jamal S. Lewis, Benjamin G. Keselowsky. Biomaterials-based Immunomodulation of Dendritic Cells. In: Biomaterials in Regenerative Medicine and the Immune System. Laura Santambrogio (Editor). Springer, publisher, Switzerland, 139 – 156.

Learn more

3. J. Sumerel, J. Lewis, A. Doraiswamy, L. F. Deravi, D. W. Wright, R. Narayan. Piezoelectric ink jet processing of materials for biological and medical applications. Biotechnology Journal. August 2006. Vol. 1. 976-987

Learn more

2. Jamal S. Lewis, Benjamin G. Keselowsky. Role of dendritic cells in response to biomaterials. In: Host Response to Biomaterials. Stephen Badylak (Editor). Academic Press, publisher, 131 – 150.

Learn more

1. Jamal S. Lewis, Benjamin G. Keselowsky. Immuno-mimetic Materials. In: Bio-inspired Materials for Biomedical Engineering. A. B. Brennan and C. M. Kirschner (Editors). Wiley, publisher, New Jersey, 357 – 370.

Learn more

Publications

35. Tu AB, Lewis JS. Biomaterial-based immunotherapeutic strategies for rheumatoid arthritis. Drug Deliv Transl Res. 2021 Aug 19:1–23. doi: 10.1007/s13346-021-01038-w. Epub ahead of print.

34. Harriman R, Lewis JS. Bioderived materials that disarm the gut mucosal immune system: Potential lessons from commensal microbiota. Acta Biomater. 2021 Jun 5:S1742-7061(21)00355-X. doi: 10.1016/j.actbio.2021.05.045. Epub ahead of print. PMID: 34098091.

32. Carstens MR, Wasserfall CH, Acharya AP, Lewis J, Agrawal N, Koenders K, Bracho-Sanchez E, Keselowsky BG. GRAS-microparticle microarrays identify dendritic cell tolerogenic marker-inducing formulations. Lab Chip. 2021 Aug 4.

31. Allen R, Ivtchenko E, Thuamsang B, Sangsuwan R, Lewis JS. Polymer-loaded hydrogels serve as depots for lactate and mimic "cold" tumor microenvironments. Biomater Sci. 2020 Oct 1. doi: 10.1039/d0bm01196g. Epub ahead of print. PMID: 33000781.

30. Sangsuwan, R., Thuamsang, B., Pacifici, N. et al. Lactate Exposure Promotes Immunosuppressive Phenotypes in Innate Immune Cells. Cel. Mol. Bioeng. (2020). https://doi.org/10.1007/s12195-020-00652-x

29. Pacifici, N., Bolandparvaz, A., & Lewis, J. S. (2020). Stimuli-Responsive Biomaterials for Vaccines and Immunotherapeutic Applications. Advanced therapeutics, 2000129. Advance online publication. https://doi.org/10.1002/adtp.202000129

28. Keselowsky, B. G., Acharya, A., & Lewis, J. S. (2020). Innate and Adaptive Immunity: The Immune Response to Foreign Materials. In Biomaterials Science (pp. 747-776). Academic Press. doi: https://doi.org/10.1016/B978-0-12-816137-1.00049-0

26. Cruz-Acuña, M., Pacifici, N., & Lewis, J. S. Vomocytosis: Too Much Booze, Base, or Calcium? mBio, 2019, doi: 10.1128/mBio.02526-19

24. Bolandparvaz, Amir et al. “Towards a nanoparticle-based prophylactic for maternal autoantibody-related autism” Nanomedicine: Nanotechnology, Biology and Medicine, 2019, doi.org/10.1016/j.nano.2019.102067

23. Allen, Riley et al. “Combinatorial, Microparticle-Based Delivery of Immune Modulators Reprograms the Dendritic Cell Phenotype and Promotes Remission of Collagen-Induced Arthritis in Mice.” ACS Bio Materials, 2019, doi: 10.1021/acsabm.9bOOO92.

22. Kakwere, Hamilton, et al. “Unimicellar Hyperstars as Multi-Antigen Cancer Nanovaccines Displaying Clustered Epitopes of Immunostimulating Peptides.” Biomaterials Science, 2018, doi:10.1039/c8bm00891d.

21. Riley P. Allen, Amir Bolandparvaz, Jeffrey A. Ma, Vishal A. Manickam, and Jamal S. Lewis. Latent, Immunosuppressive Nature of Poly(lactic-co-glycolic acid) Microparticles. ACS Biomaterials Science & Engineering 2018 4 (3), 900-918. DOI: 10.1021/acsbiomaterials.7b00831

19. Hamilton Kakwere† , Elizabeth S. Ingham†, Riley Allen†, Lisa M. Mahakian†, Sarah M. Tam†, Hua Zhang†, Matthew T. Silvestrini†, Jamal S. Lewis† , and Katherine W. Ferrara*†, PToward Personalized Peptide-Based Cancer Nanovaccines: A Facile and Versatile Synthetic Approach.

17. Keselowsky, B.G., Lewis, J.S. Dendritic cells in the host response to implanted materials. Seminars in Immunology. 2017 May: S1044-5323(16)30111-7. doi: 10.1016/j.smim.2017.04.002.

16. Zaveri, T. D., Dolgova, N. V., Lewis, J. S., Hamaker, K., Clare-Salzler, M. J., & Keselowsky, B. G. (2016). Macrophage integrins modulate response to ultra-high molecular weight polyethylene particles and direct particle-induced osteolysis. Biomaterials. doi:10.1016/j.biomaterials.2016.10.038

15. Lewis, J. S., & Allen, R. P. (2016). An introduction to biomaterial-based strategies for curbing autoimmunity. Experimental Biology and Medicine, 241(10), 1107-1115. doi:10.1177/1535370216650294

11. Toral Zaveri, Jamal S. Lewis, Natalia Dolgova, Michael Clare-Salzler, Benjamin G. Keselowsky. Integrin-Directed Modulation of Macrophage Response to Biomaterials. Biomaterials. January 2014. Vol. 35; 3504 –3515.

10. Jamal S. Lewis, Chris Roche, Ying Zhang, Benjamin G. Keselowsky. Microsphere technology offers combinatorial and local drug delivery to dendritic cells for enhancement of suppressive function. J. Mater. Chem. B. 2:2562-2574. (DOI: 10.1039/C3TB21460E). January 2014.

9. Jamal S. Lewis, Krishnendu Roy, Benjamin G. Keselowsky. Materials that harness and modulate the immune system. MRS Bulletin. January 2014. Vol. 39; 25 – 34.

8. Jamal S. Lewis, Natalia V. Dolgova, Thomas J. Chancellor, Abhinav A. Acharya, Jerome V. Karpiak, Tanmay P. Lele, Benjamin G. Keselowsky. Dendritic cell activation is influenced by cyclic mechanical strain when cultured on adhesive substrates. Biomaterials. August 2013. Vol. 34; 9063 – 9070

7. Abhinav P. Acharya, Jamal S. Lewis, Benjamin G. Keselowsky. High-throughput Parallel Particle Production for Combinatorial Encapsulation of Hydrophobic Molecules. Biomaterials. April 2013. Vol. 34; 3422 – 3430

6. Jamal S. Lewis, Patrick C. Crooks, Toral Zaveri, Benjamin G. Keselowsky. Microparticle surface modification approaches for efficient dendritic cell-targeting drug delivery for auto-immune vaccine applications. Biomaterials. June 2012. Vol. 33; 7221 – 7232

5. J S Lewis, S D Gittard, R J Narayan, C J Berry, R L Brigmon, R Ramamurti, R N Singh. Assessment of Microbial Biofilm Growth on Nanocrystalline Diamond Coatings Using a CDC Biofilm Reactor. J. Manuf. Sci. Eng. June 2010 132, 030919

4. Evelyn Bracho-Sanchez, Jamal S. Lewis, Benjamin G. Keselowsky. Biomaterials-based Immunomodulation of Dendritic Cells. In: Biomaterials in Regenerative Medicine and the Immune System. Laura Santambrogio (Editor). Springer, publisher, Switzerland, 139 – 156.

3. J. Sumerel, J. Lewis, A. Doraiswamy, L. F. Deravi, D. W. Wright, R. Narayan. Piezoelectric ink jet processing of materials for biological and medical applications. Biotechnology Journal. August 2006. Vol. 1. 976-987

2. Jamal S. Lewis, Benjamin G. Keselowsky. Role of dendritic cells in response to biomaterials. In: Host Response to Biomaterials. Stephen Badylak (Editor). Academic Press, publisher, 131 – 150.

1. Jamal S. Lewis, Benjamin G. Keselowsky. Immuno-mimetic Materials. In: Bio-inspired Materials for Biomedical Engineering. A. B. Brennan and C. M. Kirschner (Editors). Wiley, publisher, New Jersey, 357 – 370.

The Lewis Lab